Rabbit anti-TMPRSS2 Polyclonal Antibody

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Catalog NumberRD82449A

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Overview
Product NameRabbit anti-TMPRSS2 Polyclonal Antibody
Catalog NumberRD82449A
Purification MethodAffinity purification
IsotypeIgG
HostRabbit
Background

This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen Information
ImmunogenRecombinant protein of human TMPRSS2
Gene ID7113
SwissprotO15393
SynonymsD16Ertd61eEpitheliasinFLJ41954MGC6821PP9284PRSS10Serine protease 10TMPRSS2TMPRSS2 ERG FUSION GENEINCLUDEDTMPRSS2 ETV1 FUSION GENEINCLUDEDTMPS2Transmembrane protease serine 2 catalytic chainTransmembrane proteaseserine 2Transmembrane proteaseserine 2EC 3.4.219
Applications
ReactivityHuman,Mouse
Tested applicationsWB,IHC
ConjugationUnconjugated
DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200
Dilution1mg/ml
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage InstructionsStore at -20℃. Avoid repeated freeze / thaw cycles.
Research Area

Cancer, Cell Biology, Neuroscience

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